![]() The lower the oxygen permeation rate, the higher the barrier property of the bottle. When a plastic bottle consists of a very low oxygen permeation rate it is considered an oxygen barrier bottle. Measurements: OTR is measured in cc/bottle per day.Rate in Packaging: In terms of packaging, OTR is the rate at which oxygen molecules will permeate through the package wall.Permeability: All polymers are permeable to gases and vapors to different extents, and oxygen is no different. ![]() ![]() Definition: Oxygen transmission rate (OTR) is the rate at which oxygen molecules traverse through a solid material over a given time period.See how LOG’s oxygen barrier packaging solutions can support you in the development of a safe and stable product that guarantees its utmost efficiency. Besides a loss of efficacy and reduction in shelf life, exposure to oxygen can result in product discoloration, toxicity, or other pharmacological properties associated with negative side effects. Many of today’s pharmaceutical formulations, to some degree, are sensitive to oxidation. Here you can also learn more about LOG’s insights on moisture-sensitive formulations through its testing of the Water Vapor Transmission Rate and its MonoBlock® barrier solution. Within this article, LOG presents insights about OTR testing and its oxygen barrier bottle portfolio. With the growing percentage of APIs sensitive to oxygen, LOG offers a wide range of oxygen barrier packaging solutions specifically designed for oxygen-sensitive pharma formulations. ![]()
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